MRHetPen Class

An object containing the estimate produced using the heterogeneity-penalized model-averaging mode-based estimation method as well as various statistics.

Slots

Exposure

The names of the exposure variables.

Outcome

The name of the outcome variable.

Prior

The value of the prior probability of a genetic variant being a valid instrument (default is 0.5).

Estimate

The causal estimate from the heterogeneity-penalized method.

CIRange

The confidence interval for Estimate based on a grid search.

CILower

The lower limit of the confidence interval. If the confidence interval contains multiple ranges, then lower limits of all ranges will be reported.

CIUpper

The upper limit of the confidence interval. If the confidence interval contains multiple ranges, then upper limits of all ranges will be reported.

CIMin

The smallest value used in the search to find the confidence interval.

CIMax

The largest value used in the search to find the confidence interval.

CIStep

The step size used in the search to find the confidence interval.

Alpha

The significance level used in constructing the confidence interval (default is 0.05).

SNPs

The number of SNPs that were used in the calculation.