Data on lipid effects on coronary artery disease (uncorrelated variants)

Two sets of example data are included in the package: one illustrating uncorrelated variants, and the other correlated variants. These are the data on uncorrelated variants.

The variables ldlc, hdlc, trig, and chdlodds are the genetic associations with (respectively) LDL-cholesterol, HDL-cholesterol, triglycerides, and coronary heart disease (CHD) risk for 28 genetic variants reported by Waterworth et al (2010). The respective standard errors of the associations are given as ldlcse, hdlcse, trigse, and chdloddsse.

These data can be used to test out the various functions in the package.

Usage

ldlc

hdlc

hdlcse

ldlcse

trig

trigse

chdlodds

chdloddsse

lipid_effect

lipid_other

lipid_eaf

Format

An object of class numeric of length 28.

An object of class numeric of length 28.

An object of class numeric of length 28.

An object of class numeric of length 28.

An object of class numeric of length 28.

An object of class numeric of length 28.

An object of class numeric of length 28.

An object of class numeric of length 28.

An object of class character of length 28.

An object of class character of length 28.

An object of class numeric of length 28.

References

Dawn Waterworth, Sally Ricketts, ..., Manj Sandhu: Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010; 30:2264-227. doi: 10.1161/atvbaha.109.201020.